Fabian H. Klopfer

Systems Engineer & Neuroscientist

About

Two master’s degrees in computer science and neuroscience. Built a graph database storage engine from scratch in C, ran computational pipelines for deep brain stimulation surgery at University Hospital Tuebingen and high field MRI at the Max Planck Institute for Biological Cybernetics, and contributed to open source projects including scikit-learn, SHAP, and MONAI. Currently building distributed datalake systems at IBM. Interested in systems that handle complexity without cutting corners.

Selected Work

Systems from Scratch

Graph Database Storage Engine C

Record layout optimization and query algorithms, built from the ground up. 15,000 lines. · write-up

Generic Blockchain Rust

Type-generic blockchain with pluggable payloads, async networking, and cryptographic signing. · write-up

Concept Hierarchy Formation Java

Automatic type hierarchy inference in property graph databases using conceptual clustering. · write-up

Scientific Computing

Brain Microstructure Prediction Python

Conditional GAN predicting diffusion tensors from bSSFP MRI. 51M parameter model. · write-up

MEA Analysis Toolbox Python

Interactive analysis pipeline for 256-electrode neural recordings. Spectral, burst, and network analysis. · write-up

Data-Driven Biomarkers for DBS Python

Electrophysiological biomarker discovery for Parkinson's deep brain stimulation using SHAP explainability. 42 patients, 5,122 samples. · write-up